Transient corneal microcysts associated with interferon therapy

Cornea. 2005 May;24(4):480-1. doi: 10.1097/01.ico.0000151566.70731.35.


Purpose: To report transient corneal epithelial microcysts associated with interferon therapy.

Methods: Case report.

Results: Transient corneal epithelial microcysts appeared bilaterally with the onset of therapy with pegylated interferon and ribavirin for the treatment of hepatitis C. These microcysts resolved completely after discontinuation of the pegylated interferon with ribavirin therapy.

Conclusions: Pegylated interferon therapy was associated with transient corneal epithelial microcysts in our patient.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Corneal Diseases / chemically induced*
  • Corneal Diseases / pathology
  • Cysts / chemically induced*
  • Cysts / pathology
  • Drug Therapy, Combination
  • Female
  • Hepatitis C / drug therapy
  • Humans
  • Interferons / adverse effects*
  • Interferons / therapeutic use
  • Ribavirin / therapeutic use


  • Antiviral Agents
  • Ribavirin
  • Interferons