Perforated corneal hydrops treated with sulfur hexafluoride (SF6) gas and tissue adhesive

Cornea. 2005 May;24(4):503-4. doi: 10.1097/01.ico.0000151541.77618.2f.


Purpose: To report a case of a perforated acute hydrops in a mentally retarded patient that was successfully managed with intracameral sulfur hexafluoride gas and cyanoacrylate tissue adhesive.

Methods: Interventional case report.

Results: A 14-year-old mentally retarded male patient with keratoconus presented with a perforated acute hydrops. A bandage contact lens was applied. However, following a large emesis 2 days later, the aqueous leak worsened with shallowing of the anterior chamber. Under general anesthesia, sulfur hexafluoride was injected to reform the anterior chamber and cyanoacrylate tissue adhesive was applied to the perforated site and covered by a bandage contact lens and temporary tarsorrhaphy. A follow-up examination at 1 month showed a formed anterior chamber with tissue adhesive in situ and no aqueous leak.

Conclusions: The successful use of intracameral sulfur hexafluoride and tissue adhesive in the management of perforated acute hydrops may avoid emergency tectonic penetrating keratoplasty and reduce potential complications in the poorly cooperative patient.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anterior Chamber
  • Corneal Edema / complications
  • Corneal Edema / drug therapy*
  • Corneal Edema / pathology
  • Corneal Ulcer / complications
  • Corneal Ulcer / drug therapy*
  • Corneal Ulcer / pathology
  • Cyanoacrylates / therapeutic use*
  • Gases / administration & dosage*
  • Gases / therapeutic use
  • Humans
  • Injections
  • Male
  • Sulfur Hexafluoride / administration & dosage*
  • Sulfur Hexafluoride / therapeutic use
  • Tissue Adhesives / therapeutic use*
  • Treatment Outcome


  • Cyanoacrylates
  • Gases
  • Tissue Adhesives
  • Sulfur Hexafluoride