Advances in anti-viral therapeutics

Expert Opin Investig Drugs. 2005 Mar;14(3):343-8. doi: 10.1517/13543784.14.3.343.

Abstract

Hepatitis C virus (HCV) and HIV infections are of high economical importance as they have a global impact, high mortality rates and, consequently novel treatments are urgently needed. Worldwide, 170 and 34 - 46 million people are infected with HCV and HIV, respectively. HCV and HIV medications constitute the largest antiviral markets today. The efforts in fighting HCV infections are still limited to early clinical development, trying to establish proof-of-concept in man. However, in HIV, there is a better chance that some of the new drugs on new and old targets (indirect and direct antiviral targets, like CCR5 and HIV protease, respectively) will finally reach the market.

Publication types

  • Congress

MeSH terms

  • Animals
  • Antiviral Agents / chemistry
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use*
  • Drugs, Investigational / chemistry
  • Drugs, Investigational / pharmacology
  • Drugs, Investigational / therapeutic use*
  • Hepacivirus / drug effects
  • Hepatitis C / drug therapy
  • Hepatitis C / virology
  • Humans
  • London
  • Technology, Pharmaceutical / trends*

Substances

  • Antiviral Agents
  • Drugs, Investigational