Controllable preparation of Nano-MgO and investigation of its bactericidal properties

J Inorg Biochem. 2005 May;99(5):986-93. doi: 10.1016/j.jinorgbio.2004.12.022.


Samples of nano-MgO with varying particle sizes were prepared by four different methods using Mg(NO3)2.6H2O, Na2CO3, urea and ammonia as raw materials and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), low temperature N2 adsorption-desorption measurements and FT-IR spectroscopy. Bactericidal experiments with Bacillus subtilis var. niger and Staphylococcus aureus were carried out using as-synthesized nano-MgO samples and the bactericidal mechanism was also investigated. The results showed that the bactericidal efficacy of nano-MgO increases with decreasing particle size. The bactericidal efficacy of the samples was compared with that of TiO2, a common photoactive bactericidal material. The nano-MgO has better bactericidal activity, both when used directly and as an additive in an interior wall paint. Furthermore, nano-MgO is active even in the absence of irradiation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemical synthesis*
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Bacillus subtilis / drug effects
  • Magnesium Oxide / chemical synthesis*
  • Magnesium Oxide / chemistry
  • Magnesium Oxide / pharmacology*
  • Nanostructures / chemistry
  • Paint
  • Particle Size
  • Staphylococcus aureus / drug effects
  • Titanium / pharmacology


  • Anti-Bacterial Agents
  • titanium dioxide
  • Magnesium Oxide
  • Titanium