Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. I. Taxonomy, fermentation, isolation and biological activities
- PMID: 15835721
- DOI: 10.1038/ja.2005.12
Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. I. Taxonomy, fermentation, isolation and biological activities
Abstract
A new xanthone compound named retymicin (1) was isolated together with galtamycin B (2) and saquayamycin Z (3), new members of the galtamycin and saquayamycin families, respectively, and the new lumichrome derivative 1-(alpha-ribofuranosyl)-lumichrome (4) from Micromonospora strain Tü 6368, isolated from a soil sample collected in Romania. Retymicin, galtamycin B and saquayamycin Z show cytostatic effects to various human tumor cell lines whereas saquayamycin Z is also active against Gram-positive bacteria.
Similar articles
-
Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. II. Structure elucidation.J Antibiot (Tokyo). 2005 Feb;58(2):103-10. doi: 10.1038/ja.2005.13. J Antibiot (Tokyo). 2005. PMID: 15835722
-
[The antibiotic galtamycin. Its fermentation, isolation, physicochemical and biological properties].Antibiot Med Biotekhnol. 1986 Jun;31(6):428-31. Antibiot Med Biotekhnol. 1986. PMID: 3461745 Russian.
-
Cloning and sequencing of the biosynthetic gene cluster for saquayamycin Z and galtamycin B and the elucidation of the assembly of their saccharide chains.Chembiochem. 2009 May 25;10(8):1392-401. doi: 10.1002/cbic.200900054. Chembiochem. 2009. PMID: 19384899
-
Ripromycin and other polycyclic macrolactams from Streptomyces sp. Tü 6239: taxonomy, fermentation, isolation and biological properties.J Antibiot (Tokyo). 2003 Apr;56(4):364-71. doi: 10.7164/antibiotics.56.364. J Antibiot (Tokyo). 2003. PMID: 12817810
-
Arisostatins A and B, new members of tetrocarcin class of antibiotics from Micromonospora sp. TP-A0316. I. Taxonomy, fermentation, isolation and biological properties.J Antibiot (Tokyo). 2000 Mar;53(3):227-32. doi: 10.7164/antibiotics.53.227. J Antibiot (Tokyo). 2000. PMID: 10819292
Cited by
-
Tailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities.Chem Biol. 2012 May 25;19(5):647-55. doi: 10.1016/j.chembiol.2012.04.010. Chem Biol. 2012. PMID: 22633416 Free PMC article.
-
The Lichens' Microbiota, Still a Mystery?Front Microbiol. 2021 Mar 30;12:623839. doi: 10.3389/fmicb.2021.623839. eCollection 2021. Front Microbiol. 2021. PMID: 33859626 Free PMC article. Review.
-
Mintaimycins, a Group of Novel Peptide Metabolites from Micromonospora sp. C-3509.Molecules. 2022 Feb 9;27(4):1150. doi: 10.3390/molecules27041150. Molecules. 2022. PMID: 35208940 Free PMC article.
-
Screening of mutant strain Streptomyces mediolani sp. AC37 for (-)-8-O-methyltetrangomycin production enhancement.J Microbiol. 2012 Dec;50(6):1014-23. doi: 10.1007/s12275-012-2025-5. Epub 2012 Dec 30. J Microbiol. 2012. PMID: 23274989
-
Selective isolation and rapid identification of members of the genus Micromonospora.Appl Environ Microbiol. 2008 Sep;74(17):5593-7. doi: 10.1128/AEM.00303-08. Epub 2008 Jul 11. Appl Environ Microbiol. 2008. PMID: 18621873 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
