Infection by Rhodotorula sp. in children receiving treatment for malignant diseases

J Pediatr Hematol Oncol. 2005 Apr;27(4):232-3. doi: 10.1097/01.mph.0000158970.27196.c5.

Abstract

Rhodotorula sp. are commensal yeasts that may cause opportunistic infections. There have been only a few case reports of Rhodotorula fungemia in children with cancer, and in all of them the patients had a central venous catheter inserted. The authors report three nonfatal cases of fungemia by Rhodotorula in patients with post-chemotherapy neutropenia. Two of three patients required catheter removal, and a response was achieved with systemic antifungal therapy. Aggressive therapy may be required for selected high-risk patients.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antifungal Agents / therapeutic use*
  • Antineoplastic Agents / therapeutic use
  • Catheterization, Central Venous / adverse effects
  • Catheters, Indwelling / microbiology
  • Child
  • Female
  • Fungemia / drug therapy
  • Fungemia / etiology*
  • Humans
  • Leukemia, Promyelocytic, Acute / complications
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / microbiology
  • Lymphoma, T-Cell / complications
  • Lymphoma, T-Cell / drug therapy
  • Lymphoma, T-Cell / microbiology
  • Rhodotorula / isolation & purification*
  • Sarcoma, Ewing / complications
  • Sarcoma, Ewing / drug therapy
  • Sarcoma, Ewing / microbiology

Substances

  • Antifungal Agents
  • Antineoplastic Agents