Effect of chronic total coronary occlusion on treatment strategy

Am J Cardiol. 2005 May 1;95(9):1088-91. doi: 10.1016/j.amjcard.2004.12.065.


In a registry analysis of 8,004 consecutive patients presenting for diagnostic catheterization at a single institution from 1990 to 2000, chronic total occlusion (CTO) was found in 52% of patients with significant (> or = 70% diameter stenosis) coronary artery disease. Peripheral vascular disease was the strongest clinical predictor of the presence of a CTO. In a multivariate analysis, CTO was the strongest predictor against the selection of percutaneous coronary intervention (PCI) as a treatment strategy, indicating that efforts to improve the success rate of PCI in CTO may have a significant impact on management of coronary disease.

MeSH terms

  • Angioplasty, Balloon, Coronary*
  • Cardiac Catheterization
  • Chronic Disease
  • Coronary Artery Bypass*
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / surgery
  • Coronary Artery Disease / therapy*
  • Coronary Stenosis / diagnosis*
  • Coronary Stenosis / surgery
  • Coronary Stenosis / therapy*
  • Decision Making
  • Humans
  • Middle Aged
  • Odds Ratio
  • Registries