A patient with pulmonary hypertension (PH) during subacute cutaneous lupus erythematosus is described. Since the PH is characteristic of other connective tissue diseases (systemic sclerosis, Sharp syndrome), if a systemic lupus erythemtosus is coexistent, one should make a careful diagnostic screening (capillaroscopy, anti-centromere, or anti-Sc170, or anti-RNP antibodies) to show a possible overlap-syndrome.