A Pilot Study of Standardized Treatment in Geriatric Bipolar Disorder

Am J Geriatr Psychiatry. 2005 Apr;13(4):319-23. doi: 10.1176/appi.ajgp.13.4.319.


Objective: The authors sought to determine the feasibility of treating elderly adults with bipolar disorder under standardized-treatment conditions.

Methods: Thirty-one patients age 60 and older with bipolar disorder were treated in standardized pathways. Mood state was checked at each study visit with the Hamilton Rating Scale for Depression-17 item (Ham-D-17) and the Young Mania Rating Scale (YMRS).

Results: Defining "well days" as both Ham-D and YMRS scores of <or=10, the mean percentage of well days was 72.5 (range: 0%-100%) over study participation.

Conclusions: Treating older adults with bipolar disorder under standardized treatment is feasible and is associated with low symptom levels. However, most older adults with bipolar disorder do not experience sustained recovery.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bipolar Disorder / diagnosis
  • Bipolar Disorder / drug therapy*
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / drug therapy
  • Depressive Disorder, Major / psychology
  • Diagnostic and Statistical Manual of Mental Disorders
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Surveys and Questionnaires