Usefulness of low-dose dobutamine stress echocardiography for the evaluation of spontaneous recovery of stunned myocardium in patients with acute right ventricular infarction

J Am Soc Echocardiogr. 2005 Apr;18(4):351-6. doi: 10.1016/j.echo.2004.11.003.

Abstract

Right ventricular (RV) infarction (RVI) is usually associated with severe RV global dysfunction representing predominantly stunned myocardium that may respond favorably to reperfusion. We assessed the efficacy of low-dose dobutamine stress echocardiography (DSE), performed early in the course of a reperfused RVI, to predict the recovery of RV systolic and diastolic function in 3 months, documenting the recovery of stunned myocardium. In all, 27 patients with acute, successfully thrombolyzed RVI comprised the study population. All patients underwent standard echocardiography at baseline and 3 months later for evaluation of RV systolic and diastolic function. At day 5 DSE was performed for evaluation of RV contractile reserve. Of the total number of segments analyzed, 69% were detected as stunned. At baseline, RV systolic and diastolic indices were seriously impaired showing significant improvement at follow-up. RV wall-motion score index during DSE was positively correlated with the same index at follow-up. DSE is a safe and precise modality to predict recovery of stunned myocardium in the setting of RVI.

MeSH terms

  • Cardiotonic Agents*
  • Dobutamine*
  • Echocardiography, Stress*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / physiopathology*
  • Myocardial Stunning / diagnostic imaging*
  • Predictive Value of Tests

Substances

  • Cardiotonic Agents
  • Dobutamine