Prevalence and sexual risk of hepatitis C virus infection when human immunodeficiency virus was acquired through sexual intercourse among patients of the Lyon University Hospitals, France, 1992-2002

J Viral Hepat. 2005 May;12(3):330-2. doi: 10.1111/j.1365-2893.2005.00583.x.


To report the prevalence and the risk factors for hepatitis C virus (HCV) infection in a hospital cohort of 2691 sexually human immunodeficiency virus (HIV)-infected patients. The patients were enrolled in the Lyon section of the French Hospital Database on HIV between 1992 and 2002. Baseline characteristics were analysed. The detection of HCV-antibodies (Ab) was used for diagnosis. The HCV-Ab prevalence rate was 5.7 and 12.89% for individuals infected by HIV after homosexual intercourse or heterosexual intercourse, respectively. HCV-Ab was three times more frequently found among patients infected with HIV after heterosexual intercourse compared with patients infected with HIV after homosexual intercourse (adjusted OR: 3.2, 95% CI: 2.28-4.62, multiple logistic regression). The risk of HCV infection among HIV-infected individuals differed according to sexual behaviour. The determinants associated with HCV transmission through the sexual route needs to be explored further.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Cohort Studies
  • Coitus
  • Confidence Intervals
  • Female
  • France / epidemiology
  • HIV Infections / diagnosis
  • HIV Infections / epidemiology*
  • HIV Infections / transmission*
  • Hepatitis C, Chronic / epidemiology*
  • Hepatitis C, Chronic / transmission*
  • Hospitals, University
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Prevalence
  • Probability
  • Retrospective Studies
  • Risk-Taking
  • Severity of Illness Index
  • Sex Distribution
  • Sexually Transmitted Diseases / diagnosis
  • Sexually Transmitted Diseases / epidemiology*
  • Survival Rate