Overlap of pathology in paralytic rabies and axonal Guillain-Barre syndrome

Ann Neurol. 2005 May;57(5):768-72. doi: 10.1002/ana.20482.

Abstract

We describe clinical and pathological features of a case of paralytic rabies with acute axonal neuropathy that closely resembled axonal Guillain-Barre syndrome. This case emphasizes that there is overlap of both clinical and pathological features in paralytic rabies and axonal Guillain-Barre syndrome. These findings raise the possibility that infectious and autoimmune etiologies can lead to similar morphological changes in the nerves.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Campylobacter jejuni / immunology
  • Electrophysiology
  • Enzyme-Linked Immunosorbent Assay
  • Fatal Outcome
  • Guillain-Barre Syndrome / pathology*
  • Humans
  • In Situ Hybridization
  • Macrophages / pathology
  • Male
  • Microscopy, Confocal
  • Microscopy, Electron
  • Middle Aged
  • Muscle, Skeletal / pathology
  • Paralysis / pathology
  • Rabies / pathology*
  • Spinal Cord / pathology
  • Spinal Nerve Roots / pathology