The role of vitamin D in protecting type 1 diabetes mellitus

Diabetes Metab Res Rev. Jul-Aug 2005;21(4):338-46. doi: 10.1002/dmrr.557.


The relationship between autoimmune diabetes or type 1 diabetes mellitus and vitamin D has been reported in the literature. Many factors, environmental and genetic, have been known, as risk factors, to cause both type 1 diabetes and vitamin D deficiency. Vitamin D treatment has improved or prevented type 1 diabetes mellitus in animals and humans. Vitamin D also has been known to protect from autoimmune diseases in animal models. Therefore, it would be interesting to review the role of vitamin D in type 1 diabetes mellitus.

Publication types

  • Review

MeSH terms

  • Calcitriol / therapeutic use
  • Diabetes Mellitus, Type 1 / epidemiology
  • Diabetes Mellitus, Type 1 / genetics
  • Diabetes Mellitus, Type 1 / prevention & control*
  • Humans
  • Models, Genetic
  • Risk Factors
  • Vitamin D / therapeutic use*


  • Vitamin D
  • Calcitriol