Abstract
In Portugal erythromycin resistance of 26.6% (n = 352) remained constant during 1998 to 2003, however in 1998 the MLS(B) phenotype dominated (85%), whereas in 2003 the M phenotype prevailed (77%). A decline in T12/emm22 MLS(B) isolates could partially explain the drop in this phenotype, but the rise of the M phenotype was not due to clonal expansion.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacterial Proteins / genetics*
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Drug Resistance, Bacterial
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Humans
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Macrolides / pharmacology*
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Membrane Proteins / genetics*
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Phenotype
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Portugal / epidemiology
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Streptococcal Infections / drug therapy
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Streptococcal Infections / epidemiology
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Streptococcal Infections / microbiology
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Streptococcus pyogenes / drug effects*
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Streptococcus pyogenes / genetics*
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Tetracycline Resistance
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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Emm22 protein,Streptococcus pyogenes
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Macrolides
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Membrane Proteins