Acustimulation wrist bands are not effective for the control of chemotherapy-induced nausea in women with breast cancer

J Pain Symptom Manage. 2005 Apr;29(4):376-84. doi: 10.1016/j.jpainsymman.2004.07.007.


This experiment examined the efficacy of an acustimulation wrist band for the relief of chemotherapy-induced nausea using a randomized three-arm clinical trial (active acustimulation, sham acustimulation, and no acustimulation) in 96 women with breast cancer who experienced nausea at their first chemotherapy treatment. Five outcomes related to wrist band efficacy (acute nausea, delayed nausea, vomiting, QOL, and total amount of antiemetic medication used) were examined. The five outcomes were examined separately using analysis of covariance controlling for age and severity of past nausea. There were no significant differences in any of these study measures among the three treatment conditions (P>0.1 for all). Study results do not support the hypothesis that acustimulation bands are efficacious as an adjunct to pharmacological antiemetics for control of chemotherapy-related nausea in female breast cancer patients.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acupuncture Therapy / methods*
  • Adult
  • Aged
  • Antiemetics / therapeutic use
  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Breast Neoplasms / drug therapy
  • Combined Modality Therapy / methods
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Middle Aged
  • Nausea / chemically induced*
  • Nausea / drug therapy
  • Nausea / prevention & control*
  • Transcutaneous Electric Nerve Stimulation / methods*
  • Wrist / innervation
  • Wrist / physiopathology


  • Antiemetics
  • Antineoplastic Agents
  • Doxorubicin
  • Cyclophosphamide