Flavonoids as developmental regulators

Curr Opin Plant Biol. 2005 Jun;8(3):317-23. doi: 10.1016/j.pbi.2005.03.005.


Flavonoids, usually regarded as dispensable phytochemicals derived from plant secondary metabolism, play important roles in the biology of plants by affecting several developmental processes. Bioactive flavonoids also signal to microbes, serve as allelochemicals and are important nutraceuticals in the animal diet. Despite the significant progress made in identifying flavonoid pathway genes and regulators, little is currently known about the protein targets of flavonoids in plant or animal cells. Recently, there have been advances in our understanding of the roles that flavonoids play in developmental processes of plants. The multiple cellular roles of flavonoids can reflect their chemical diversity, or might suggest the existence of cellular targets shared between many of these seemingly disparate processes.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Antineoplastic Agents, Phytogenic / pharmacology
  • Biological Transport
  • Flavonoids / chemistry
  • Flavonoids / pharmacology
  • Flavonoids / physiology*
  • Germination / physiology
  • Indoleacetic Acids / metabolism
  • Molecular Structure
  • Plant Development*
  • Plant Growth Regulators / metabolism
  • Plant Growth Regulators / physiology*
  • Pollen
  • Signal Transduction


  • Antineoplastic Agents, Phytogenic
  • Flavonoids
  • Indoleacetic Acids
  • Plant Growth Regulators