Non-homogeneous hyperechogenic echo pattern three days after frozen embryo transfer is associated with lower pregnancy rates

Clin Exp Obstet Gynecol. 2005;32(1):15-8.

Abstract

Objective: To evaluate the association of mid-luteal phase echo patterns and pregnancy rates (PRs) following frozen embryo transfer (ET).

Methods: Sonographic evaluation of endometrial echo patterns was performed three days after ET in the first frozen ET cycle of women < 40 years of age who used their own oocytes as well as all donor oocyte recipients.

Results: The distribution of echo patterns and clinical PRs were similar in women using their own eggs and women who used donor oocytes; therefore all data was combined. The clinical PR was 49.5% with a hyperechogenic echo pattern vs 38.8% with a non-hyperechogenic pattern, p = .007.

Conclusion: A larger study of frozen ET and mid-luteal echo pattern now demonstrates conclusions similar to the data from fresh ET in hyperstimulated in vitro fertilization (IVF)-ET cycles in that failure to attain a hyperechogenic echo pattern three days after ET is associated with lower pregnancy rates.

MeSH terms

  • Adult
  • Cryopreservation*
  • Embryo Transfer*
  • Endometrium / diagnostic imaging*
  • Estrogens / therapeutic use
  • Female
  • Fertility Agents, Female / therapeutic use
  • Humans
  • Leuprolide / therapeutic use
  • Luteal Phase / physiology*
  • Pregnancy
  • Pregnancy Rate*
  • Progesterone / therapeutic use
  • Prospective Studies
  • Tissue Donors
  • Ultrasonography, Doppler, Color

Substances

  • Estrogens
  • Fertility Agents, Female
  • Progesterone
  • Leuprolide