Predictive value of laryngeal pseudosulcus for gastroesophageal reflux in pediatric patients

Int J Pediatr Otorhinolaryngol. 2005 Aug;69(8):1109-12. doi: 10.1016/j.ijporl.2005.02.022.


Objective: To determine if the presence of laryngeal pseudosulcus is a good predictor of reflux in children.

Methods: A retrospective review of clinical photographs of 66 children undergoing direct laryngoscopy for airway symptoms for the presence of laryngeal pseudosulcus. Its presence was correlated with positive reflux tests: 24 h pH monitoring, gastric scintiscan, barium swallow, and esophageal biopsy.

Results: Fifty-six patients had a positive reflux test, and 89% of these had pseudosulcus. Seventy percent of the reflux-negative group (N=10) had no pseudosulcus. Sensitivity and specificity were 89% and 70%, respectively.

Conclusions: On its own the presence of pseudosulcus has marginal predictive use, but it is found more frequently among reflux-positive children and may be a useful marker to add to existing visual scoring systems.

MeSH terms

  • Adolescent
  • Bronchoscopy
  • Child
  • Child, Preschool
  • Female
  • Gastric Acidity Determination
  • Gastroesophageal Reflux / complications*
  • Gastroesophageal Reflux / diagnosis*
  • Humans
  • Infant
  • Laryngeal Edema / diagnosis*
  • Laryngeal Edema / etiology*
  • Laryngoscopy
  • Male
  • Predictive Value of Tests
  • Retrospective Studies
  • Sensitivity and Specificity