Mucispirillum schaedleri gen. nov., sp. nov., a spiral-shaped bacterium colonizing the mucus layer of the gastrointestinal tract of laboratory rodents

Int J Syst Evol Microbiol. 2005 May;55(Pt 3):1199-1204. doi: 10.1099/ijs.0.63472-0.


The mammalian gastrointestinal tract is covered by a layer of mucus that can harbour a range of bacterial species specifically adapted to colonize this ecological niche. Examination of 110 bacterial isolates cultivated from the gastrointestinal tract of 23 mice revealed the presence of a subgroup of 30 isolates that did not correspond genetically with genera commonly associated with this site, i.e. members of the epsilon-Proteobacteria such as Helicobacter and Campylobacter species. Instead this group of isolates was found to lie within the phylum Deferribacteres, a completely distinct lineage in the domain Bacteria. There was a high level of consensus in results obtained from the phenotypic and genotypic characterization of a number of the isolates, which showed they were distinct from other members of the Deferribacteres. As such, they are proposed to constitute a new genus and species, Mucispirillum schaedleri gen. nov., sp. nov. These organisms are anaerobic, Gram-negative, spiral-shaped rods with bipolar flagella. The type strain is HRI I17(T) (= ATCC BAA-1009(T) = ACM 5223(T)).

MeSH terms

  • Anaerobiosis
  • Animals
  • Bacterial Proteins / analysis
  • Bacterial Proteins / isolation & purification
  • Campylobacter / classification
  • Campylobacter / genetics
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / isolation & purification
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / isolation & purification
  • Flagella / physiology
  • Gastrointestinal Tract / microbiology*
  • Genes, rRNA
  • Gentian Violet
  • Gram-Negative Anaerobic Straight, Curved, and Helical Rods / classification*
  • Gram-Negative Anaerobic Straight, Curved, and Helical Rods / cytology
  • Gram-Negative Anaerobic Straight, Curved, and Helical Rods / isolation & purification*
  • Gram-Negative Anaerobic Straight, Curved, and Helical Rods / physiology
  • Helicobacter / classification
  • Helicobacter / genetics
  • Mice
  • Molecular Sequence Data
  • Mucus / microbiology*
  • Phenazines
  • Phylogeny
  • Proteome / analysis
  • RNA, Bacterial / genetics
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA


  • Bacterial Proteins
  • DNA, Bacterial
  • DNA, Ribosomal
  • Gram's stain
  • Phenazines
  • Proteome
  • RNA, Bacterial
  • RNA, Ribosomal, 16S
  • Gentian Violet

Associated data

  • GENBANK/AF059186
  • GENBANK/AF059187
  • GENBANK/AF059188
  • GENBANK/AF059189
  • GENBANK/AF059190
  • GENBANK/AY387668
  • GENBANK/AY387669
  • GENBANK/AY387670
  • GENBANK/AY387671