Effect of garlic (Allium sativum) oil on exercise tolerance in patients with coronary artery disease

Indian J Physiol Pharmacol. 2005 Jan;49(1):115-8.


The effect of six weeks garlic oil administration was observed on cardiac performance and exercise tolerance in 30 patients of coronary artery disease. After initial treadmill stress test, they were administered garlic oil in the dose of four capsules twice a day for 6 weeks and treadmill stress test was repeated. Garlic significantly (P<0.01) reduced heart rate at peak exercise and also significantly reduced the work load upon the heart resulting in better exercise tolerance (P<0.05) as compared to the initial test. It appears to be a good adaptogen to be utilized in patients with coronary artery disease.

Publication types

  • Comparative Study

MeSH terms

  • Blood Pressure / drug effects
  • Blood Pressure / physiology
  • Coronary Artery Disease / drug therapy*
  • Coronary Artery Disease / physiopathology
  • Exercise Tolerance / drug effects*
  • Exercise Tolerance / physiology
  • Garlic*
  • Heart Rate / drug effects
  • Heart Rate / physiology
  • Humans
  • Male
  • Middle Aged
  • Phytotherapy* / methods
  • Plant Oils / isolation & purification
  • Plant Oils / therapeutic use*


  • Plant Oils