Long-term use of acid suppression started inappropriately during hospitalization

Aliment Pharmacol Ther. 2005 May 15;21(10):1203-9. doi: 10.1111/j.1365-2036.2005.02454.x.


Background: Practitioners routinely misuse acid suppression medications on general medical floors and inappropriately continue the drug at discharge.

Aims: To: (i) retrospectively study the appropriateness of acid suppression use on the general medical floors; (ii) characterize the patient population discharged on unnecessary acid suppression and (iii) evaluate whether patients discharged on unnecessary acid suppression continue the medicine long term.

Methods: Retrospective chart review of general medical patients admitted to an in-patient teaching service over 6 consecutive months.

Results: About 60% of patients lacked an indication for initiation of acid suppression and 34% of these patients were discharged on the medicine. The only independent predictor of continuation of acid suppression at discharge was longer length of stay. Multivariate analysis did not identify a characteristic distinguishing those patients discharged inappropriately on acid suppression. At 3 and 6 months of follow-up, 80% and 50% of patients, respectively, remained on acid suppression therapy without an appropriate indication.

Conclusions: Our data verifies that practitioners routinely start general medical in-patients on acid suppression without an appropriate indication. Many of these prescriptions are continued at discharge for no apparent reason, leading to their long-term misuse.

MeSH terms

  • Aged
  • Antacids / administration & dosage*
  • Drug Administration Schedule
  • Drug Prescriptions / standards
  • Drug Utilization Review*
  • Follow-Up Studies
  • Health Services Misuse*
  • Hospitals, Teaching / standards*
  • Humans
  • Length of Stay
  • Michigan
  • Middle Aged
  • Patient Discharge / standards*
  • Retrospective Studies
  • Self Administration


  • Antacids