Development of structures and transport functions in the mouse placenta

Physiology (Bethesda). 2005 Jun;20:180-93. doi: 10.1152/physiol.00001.2005.


The placenta is essential for sustaining the growth of the fetus during gestation, and defects in its function result in fetal growth restriction or, if more severe, fetal death. Several molecular pathways have been identified that are essential for development of the placenta, and mouse mutants offer new insights into the cell biology of placental development and physiology of nutrient transport.

Publication types

  • Review

MeSH terms

  • Animals
  • Female
  • Mice
  • Mice, Mutant Strains
  • Placenta / physiology*
  • Placenta Diseases / genetics
  • Placenta Diseases / physiopathology*
  • Pregnancy