The cases presented are of three children who responded well to Sanicula aqua. I have used the exact words of the patients or their mothers. All 3 are: firstborn girls, tall and very thin with blue-green eyes. Two with recurrent otitis media with perforated tympanic membrane and smell of rotting fish, the third atopic eczema and asthma. The case analyses, materia medica of Sanicula aqua and the creation of a remedy heuristic, are discussed.