The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: Androgen-receptor cofactors and bypass pathways

BJU Int. 2005 Jun;95(9):1327-35. doi: 10.1111/j.1464-410X.2005.05527.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antineoplastic Agents, Hormonal / therapeutic use*
  • DNA-Binding Proteins / metabolism
  • Drug Resistance, Neoplasm
  • Histone Acetyltransferases
  • Humans
  • Interleukin-6 / metabolism
  • Janus Kinase 1
  • Male
  • Mitogen-Activated Protein Kinase 3 / metabolism*
  • Nuclear Receptor Coactivator 1
  • Nuclear Receptor Coactivator 2
  • Phosphatidylinositol 3-Kinases / metabolism
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / metabolism*
  • Protein-Tyrosine Kinases / metabolism
  • Receptors, Androgen / metabolism*
  • STAT3 Transcription Factor
  • Signal Transduction / physiology*
  • Trans-Activators / metabolism
  • Transcription Factors / metabolism

Substances

  • Antineoplastic Agents, Hormonal
  • DNA-Binding Proteins
  • Interleukin-6
  • Nuclear Receptor Coactivator 2
  • Receptors, Androgen
  • STAT3 Transcription Factor
  • STAT3 protein, human
  • Trans-Activators
  • Transcription Factors
  • Histone Acetyltransferases
  • NCOA1 protein, human
  • Nuclear Receptor Coactivator 1
  • Phosphatidylinositol 3-Kinases
  • Protein-Tyrosine Kinases
  • JAK1 protein, human
  • Janus Kinase 1
  • Mitogen-Activated Protein Kinase 3