Sciatic nerve enlargement in the Klippel-Trenaunay-Weber syndrome

Br J Plast Surg. 2005 Jun;58(4):565-8. doi: 10.1016/j.bjps.2004.11.005.


The case of a 35-year-old woman with Klippel-Trenaunay-Weber syndrome (KTWS) showing clinical symptoms of a peroneal nerve lesion is presented. An immense nerve enlargement along most of the sciatic, peroneal and tibial nerve was found to be due to a lipoma arising from the epi- and perineurium. Treatment consisted of extensive microsurgical neurolysis and excision of the tumor resulting in decompression of the affected nerves. Although rare, a perineural lipoma should be kept in mind in patients with KTWS showing neurological abnormalities.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Decompression, Surgical / methods
  • Female
  • Humans
  • Klippel-Trenaunay-Weber Syndrome / diagnosis
  • Klippel-Trenaunay-Weber Syndrome / surgery*
  • Lipoma / diagnosis
  • Lipoma / surgery*
  • Microsurgery / methods
  • Peroneal Neuropathies / diagnosis
  • Peroneal Neuropathies / surgery
  • Sciatic Neuropathy / diagnosis
  • Sciatic Neuropathy / surgery*