Transepidermal water loss dynamics of human vulvar and thigh skin

Skin Pharmacol Physiol. May-Jun 2005;18(3):139-43. doi: 10.1159/000084911.

Abstract

Refinement in procedures to assess skin surface water loss (SSWL) dynamics of the vulvar skin on a large sample of subjects (60) is described and compared to another semi-occluded skin site, the inner thigh. Vulvar SSWL significantly decreased over a 30-min period from 46.2 +/- 2.6 (SE) to 24.7 +/- 1.6 g m(-2) h (p < 0.001). The inner thigh, another semi-occluded region, showed no similar pattern for SSWL (6.2 +/- 0.3 to 6.6 +/- 0.5 g m(-2) h), and the values were significantly less than those for vulvar skin. There was no significant effect of age, body mass index or atopic status on vulvar SSWL.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aging / physiology
  • Body Mass Index
  • Clothing
  • Epidermis / physiology
  • Female
  • Humans
  • Skin Physiological Phenomena*
  • Thigh
  • Vulva / physiology*
  • Water Loss, Insensible / physiology*