Factors affecting morbidity and mortality in biliary tract surgery

World J Surg. 1992 May-Jun;16(3):536-40. doi: 10.1007/BF02104465.


Thirty-six clinical and laboratory parameters in 770 consecutive patients undergoing biliary tract surgery over a 3 year period were analyzed in an effort to define the patients at greatest risk. Twelve parameters had a significant correlation with hospital mortality, while multivariate analysis revealed that septic shock, malignant obstruction, serum albumin less than 3.0 gm%, history of hypertension, and plasma urea nitrogen greater than 20 mg% had an independent significance in predicting postoperative mortality. The presence of more than 2 of these risk factors identified a group of patients with an 18% mortality rate. It is for this group of patients that adequate pre-operative preparation such as fluid resuscitation, prophylactic antibiotics, and nutritional support are essential. The controversial preoperative biliary drainage might be only indicated in this group of patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biliary Tract Surgical Procedures / mortality*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications
  • Regression Analysis
  • Risk Factors
  • Taiwan / epidemiology
  • Treatment Outcome