Genotype and phenotype relation in inflammatory bowel disease

J Gastroenterol. 2005 Mar:40 Suppl 16:21-4. doi: 10.1007/BF02990574.

Abstract

Genotype-phenotype analysis helps us to discriminate among various subgroups of IBD and consequently helps us to understand the etiology and pathogenesis as well as develop effective treatments for each subgroup of IBD.

MeSH terms

  • Adolescent
  • Adult
  • Colitis, Ulcerative / genetics
  • Crohn Disease / genetics
  • Genetic Predisposition to Disease
  • Genotype
  • HLA-DR Antigens / genetics
  • HLA-DRB1 Chains
  • Humans
  • Inflammatory Bowel Diseases / genetics*
  • Intracellular Signaling Peptides and Proteins / genetics
  • Middle Aged
  • Nod2 Signaling Adaptor Protein
  • Organic Cation Transport Proteins / genetics
  • Phenotype
  • Solute Carrier Family 22 Member 5

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains
  • Intracellular Signaling Peptides and Proteins
  • NOD2 protein, human
  • Nod2 Signaling Adaptor Protein
  • Organic Cation Transport Proteins
  • SLC22A5 protein, human
  • Solute Carrier Family 22 Member 5