Treatment options for status epilepticus

Curr Opin Pharmacol. 2005 Jun;5(3):334-9. doi: 10.1016/j.coph.2005.04.003.


Status epilepticus is a neurological emergency requiring prompt pharmacological intervention. Recent advances in the treatment of this condition include the introduction of treatment algorithms that are tailored more specifically to clinical situations, a trend towards more aggressive therapies if initial treatment with front-line agents fail, and a better understanding of the role of treatment for patients in status epilepticus in the out-of-hospital setting.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adult
  • Animals
  • Anticonvulsants / pharmacokinetics
  • Anticonvulsants / therapeutic use*
  • GABA Modulators / pharmacokinetics
  • GABA Modulators / therapeutic use*
  • Half-Life
  • Humans
  • Lorazepam / pharmacokinetics
  • Lorazepam / therapeutic use*
  • Meta-Analysis as Topic
  • Randomized Controlled Trials as Topic
  • Status Epilepticus / drug therapy*
  • Status Epilepticus / epidemiology
  • United States / epidemiology


  • Anticonvulsants
  • GABA Modulators
  • Lorazepam