Pregnancy unmasking lymphangioleiomyomatosis

J Assoc Physicians India. 2004 Oct;52:828-30.


A 30 year-old housewife presented with cough and shortness of breath which progressed during her ensuing pregnancy, culminating in a still-birth at 9 months of gestation and requiring her hospitalisation in the immediate postpartum period. HRCT scan of the thorax showed thin-walled cysts and open lung biopsy confirmed the clinical impression of lymphangioleiomyomatosis. She was put on oral medroxyprogesterone acetate. After disease flare-up in the postpartum period her symptoms have stabilised.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Female
  • Humans
  • Lymphangioleiomyomatosis / diagnosis
  • Lymphangioleiomyomatosis / drug therapy
  • Lymphangioleiomyomatosis / physiopathology*
  • Medroxyprogesterone Acetate / therapeutic use
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / drug therapy
  • Pregnancy Complications / physiopathology*


  • Antineoplastic Agents, Hormonal
  • Medroxyprogesterone Acetate