Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5

Chembiochem. 2005 Jul;6(7):1173-7. doi: 10.1002/cbic.200500005.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology*
  • Cell Culture Techniques
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology*
  • HeLa Cells
  • Humans
  • Kinesin / antagonists & inhibitors*
  • Mitosis / drug effects
  • Pyrimidines / chemistry*
  • Pyrimidines / pharmacology
  • Structure-Activity Relationship
  • Thiones / chemistry*
  • Thiones / pharmacology

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • KIF11 protein, human
  • Pyrimidines
  • Thiones
  • monastrol
  • Kinesin