In vitro activities of amphotericin B and voriconazole against aleurioconidia from Aspergillus terreus

Antimicrob Agents Chemother. 2005 Jun;49(6):2539-40. doi: 10.1128/AAC.49.6.2539-2540.2005.

Abstract

This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 microg/ml and 5 microg/ml with amphotericin B and 1 microg/ml and 2 microg/ml with voriconazole.

Publication types

  • Comparative Study

MeSH terms

  • Amphotericin B / pharmacology*
  • Antifungal Agents / pharmacology*
  • Aspergillus / drug effects
  • Aspergillus / growth & development*
  • Humans
  • Hyphae / drug effects
  • Hyphae / growth & development
  • Microbial Sensitivity Tests
  • Pyrimidines / pharmacology*
  • Triazoles / pharmacology*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Amphotericin B
  • Voriconazole