How Guillain-Barre patients experience their functioning after 1 year

Acta Neurol Scand. 2005 Jul;112(1):51-6. doi: 10.1111/j.1600-0404.2005.00429.x.


Objective: To analyze how the patient himself perceives his physical and social situation 1 year after Guillain-Barre syndrome (GBS).

Material and method: The Dutch patients who participated in an international multicenter trial were asked to complete a self-administered questionnaire containing questions on their physical status at homecoming and at 12 months, as well as questions dealing with various aspects of their social condition.

Results: Ninety patients participated. Up to 72% had sensory disturbances and loss of power in part of the arms and up to 89% in part of the legs at homecoming. At 12 months, a significant improvement had occurred, but residua were perceived in 36 and 67%, respectively. The residua ranged from irritating to seriously disturbing in up to 49%, and only 33% felt completely cured. Furthermore, 32% had changed their work due to GBS, 30% did not function at home as well as before and 52% had altered their leisure activities.

Conclusion: One year after the onset of GBS, a considerable number of patients still perceived a decrease of power and sensation with an often disturbing effect. GBS had an evident impact on daily life and social well-being.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Activities of Daily Living
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Disability Evaluation
  • Disease Progression
  • Female
  • Guillain-Barre Syndrome / drug therapy
  • Guillain-Barre Syndrome / epidemiology*
  • Guillain-Barre Syndrome / psychology*
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Netherlands / epidemiology
  • Paresis / epidemiology
  • Quality of Life / psychology
  • Recovery of Function / drug effects*
  • Recovery of Function / physiology
  • Sensation Disorders / epidemiology
  • Surveys and Questionnaires*
  • Time Factors
  • Treatment Outcome


  • Immunoglobulins, Intravenous
  • Methylprednisolone