Coordinate gene regulation by two different catenins

Dev Cell. 2005 Jun;8(6):795-6. doi: 10.1016/j.devcel.2005.05.003.

Abstract

In this issue of Developmental Cell, McCrea and colleagues report that p120-catenin regulates the same Wnt target genes as beta-catenin in the Xenopus embryo (). These findings raise the exciting possibility that these two related proteins function in parallel to mediate cadherin-associated regulation of gene expression.

Publication types

  • Comment

MeSH terms

  • Animals
  • Catenins
  • Cell Adhesion Molecules / physiology*
  • Cytoskeletal Proteins / physiology*
  • Embryo, Nonmammalian
  • Gene Expression Regulation, Developmental / physiology*
  • Intercellular Signaling Peptides and Proteins / genetics
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Phosphoproteins / physiology*
  • Trans-Activators / physiology*
  • Wnt Proteins
  • Xenopus
  • Xenopus Proteins
  • beta Catenin

Substances

  • CTNNB1 protein, Xenopus
  • Catenins
  • Cell Adhesion Molecules
  • Cytoskeletal Proteins
  • Intercellular Signaling Peptides and Proteins
  • Phosphoproteins
  • Trans-Activators
  • Wnt Proteins
  • Xenopus Proteins
  • beta Catenin
  • delta catenin