In the face of the serious problem of lack of access to health care in the United States, with over 45 million uninsured,1 there exist many models of collaborative local programs serving the uninsured. One such approach is the student-run free clinic, small projects managed by health professional students, supervised by licensed health professionals, offering free health services to those without health access. The purpose of this article is to describe the UCSD Student-Run Free Clinic Project, its history, mission, partners, clinical services, curriculum, funding, replicability, outcomes, elements of success, transdisciplinary nature, and hopes for the future.