Bioactive stilbene dimers from Gnetum cleistostachyum

Nat Prod Res. 2005 Jul;19(5):443-8. doi: 10.1080/14786410412331271041.

Abstract

Two new stilbene dimers, named bisisorhapontigenin A (1) and cis shegansu B (2), together with gnetuhainin P (3) and gnetulin (4), were isolated from the lianas of Gnetum cleistostachyum C. Y. Cheng. Their structures were elucidated by means of spectroscopic evidences, including UV, IR, MS, 1H NMR, 13C NMR, NOE and 2D NMR, respectively. The pharmacological activities of compounds 1, 2 and 3 also have been tested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / chemistry*
  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants / chemistry*
  • Antioxidants / pharmacology
  • Cells, Cultured
  • Gnetum / chemistry*
  • Macrophages / drug effects
  • Mice
  • Molecular Structure
  • Stilbenes / chemistry*
  • Stilbenes / pharmacology*

Substances

  • Anti-Inflammatory Agents
  • Antioxidants
  • Stilbenes