Lidocaine gel versus combined topical anesthesia using bupivacaine, oxybuprocaine and diclofenac eyedrops in cataract surgery

Ophthalmologica. 2005 May-Jun;219(3):167-70. doi: 10.1159/000085249.

Abstract

Purpose: To assess the safety and efficacy of two topical anesthesia regimes for cataract surgery.

Methods: 21 patients received a combination of 4 times bupivacaine 0.5, oxybuprocaine and diclofenac eyedrops, 18 patients were given a single topical application of lidocaine gel 2%. A single intracameral injection of lidocaine 1% was administered to all subjects.

Results: The extent to which the surgeon was bothered by patient motility was graded as low in about two thirds of all procedures. Patients reported lower intraoperative pain levels with a single application of lidocaine gel supplemented with intracameral lidocaine than with a fourfold application of the combination topical anesthesia plus intracameral anesthesia.

Conclusions: A single application of lidocaine gel 2% combined with intracameral anesthesia provides at least as good analgesia than multiple administration of combined topical anesthesia supplemented with intracameral anesthesia and is equally safe.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Analgesia
  • Anesthesia, Local / methods*
  • Anesthetics, Combined / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
  • Bupivacaine / administration & dosage
  • Diclofenac / administration & dosage*
  • Double-Blind Method
  • Eye Movements
  • Female
  • Gels
  • Humans
  • Injections
  • Lens Implantation, Intraocular
  • Lidocaine / administration & dosage*
  • Male
  • Ophthalmic Solutions
  • Phacoemulsification*
  • Procaine / administration & dosage
  • Procaine / analogs & derivatives*
  • Safety
  • Treatment Outcome

Substances

  • Anesthetics, Combined
  • Anesthetics, Local
  • Anti-Inflammatory Agents, Non-Steroidal
  • Gels
  • Ophthalmic Solutions
  • Diclofenac
  • Procaine
  • Lidocaine
  • benoxinate
  • Bupivacaine