Vogt-Koyanagi-Harada disease associated with interferon-A and ribavirin therapy for chronic hepatitis C infection

Konstantinos Papastathopoulos; Evridiki Bouzas; George Naoum; Ioannis Vergados; Sotirios Tsiodras

doi:10.1016/j.jinf.2005.05.005

Vogt-Koyanagi-Harada disease associated with interferon-A and ribavirin therapy for chronic hepatitis C infection

J Infect. 2006 Feb;52(2):e59-61. doi: 10.1016/j.jinf.2005.05.005. Epub 2005 Jun 13.

Authors

Konstantinos Papastathopoulos¹, Evridiki Bouzas, George Naoum, Ioannis Vergados, Sotirios Tsiodras

Affiliation

¹ Medical Retina Unit, First Department of Ophthalmology, Henry Dunant Hospital, 107 Mesogion Avenue, 11526 Athens, Greece.

PMID: 15951019
DOI: 10.1016/j.jinf.2005.05.005

Abstract

A rare case of Vogt-Koyanagi-Harada disease associated with ribavirin and interferon-alpha treatment for chronic hepatitis C infection is presented. The potential role of interferon and/or ribavirin therapy is discussed. Physicians should be aware of the association between interferon-alpha and ribavirin use for hepatitis C infection and the development of Harada's disease. Close monitoring of such patients for ocular side effects is necessary.

Publication types

Case Reports

MeSH terms

Adrenal Cortex Hormones / administration & dosage
Adult
Antiviral Agents / adverse effects*
Antiviral Agents / therapeutic use
Female
Fluorescein Angiography
Hepatitis C, Chronic / drug therapy*
Humans
Interferon-alpha / adverse effects*
Interferon-alpha / therapeutic use
Retinal Detachment / chemically induced
Retinal Detachment / diagnosis
Retinal Detachment / pathology
Ribavirin / adverse effects*
Ribavirin / therapeutic use
Treatment Outcome
Uveomeningoencephalitic Syndrome / chemically induced*
Uveomeningoencephalitic Syndrome / drug therapy

Substances

Adrenal Cortex Hormones
Antiviral Agents
Interferon-alpha
Ribavirin