Role of relaxin in maternal renal vasodilation of pregnancy

Ann N Y Acad Sci. 2005 May;1041:147-54. doi: 10.1196/annals.1282.022.


The remarkable hemodynamic changes of normal pregnancy are briefly reviewed. In addition, new findings and current concepts related to the underlying hormonal and molecular mechanisms are presented. Finally, work that is in progress as well as future directions is briefly discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Female
  • Hemodynamics
  • Humans
  • Kidney / blood supply*
  • Kidney / metabolism*
  • Kidney / physiology
  • Pregnancy / physiology*
  • Relaxin / metabolism*
  • Vasodilation / physiology*


  • Relaxin