The effect of pregnancy on renal function: physiology and pathophysiology

Am J Med Sci. 1992 Mar;303(3):184-205. doi: 10.1097/00000441-199203000-00011.

Abstract

Marked changes in renal function occur with pregnancy. We present a summary of these changes in this review and give insight into possible mechanisms if they are known. Controversies exist regarding the therapy of pregnancy-induced hypertension and asymptomatic and recurrent bacteriuria. The current views on these topics are given. Specific renal diseases are summarized, including transplantation, and optimum management strategies and maternal and fetal prognosis during pregnancy are given.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / therapeutic use
  • Eclampsia / physiopathology
  • Female
  • Humans
  • Hypertension / drug therapy
  • Hypertension / physiopathology
  • Kidney / physiology*
  • Kidney / physiopathology
  • Kidney Diseases / physiopathology*
  • Pre-Eclampsia / physiopathology
  • Pregnancy / physiology*
  • Pregnancy Complications / physiopathology*
  • Pregnancy Complications, Cardiovascular / drug therapy
  • Pregnancy Complications, Cardiovascular / physiopathology
  • Pregnancy Complications, Infectious / physiopathology
  • Urinary Tract Infections / physiopathology

Substances

  • Antihypertensive Agents