Rotavirus antigenemia in children with encephalopathy accompanied by rotavirus gastroenteritis

T Nakagomi; O Nakagomi

doi:10.1007/s00705-005-0565-2

Rotavirus antigenemia in children with encephalopathy accompanied by rotavirus gastroenteritis

Arch Virol. 2005 Sep;150(9):1927-31. doi: 10.1007/s00705-005-0565-2. Epub 2005 Jun 15.

Authors

T Nakagomi¹, O Nakagomi

Affiliation

¹ Department of Microbiology, Akita University School of Medicine, Akita, Japan. tnakagom@net.nagasaki-u.ac.jp

PMID: 15959833
DOI: 10.1007/s00705-005-0565-2

Abstract

Rotavirus antigen was detected in acute phase sera from 5 of 8 children with rotavirus-associated encephalopathy, confirming antigenemia. However, antigen was not detected in cerebrospinal fluid, failing to provide added evidence of invasion to the brain.

MeSH terms

Antigens, Viral / blood*
Child
Child, Preschool
Encephalitis, Viral / blood*
Encephalitis, Viral / cerebrospinal fluid
Encephalitis, Viral / etiology
Enzyme-Linked Immunosorbent Assay
Female
Gastroenteritis / blood*
Gastroenteritis / complications
Humans
Infant
Male
RNA, Viral / cerebrospinal fluid
Reverse Transcriptase Polymerase Chain Reaction
Rotavirus / genetics
Rotavirus / immunology*
Rotavirus Infections / blood*
Rotavirus Infections / complications

Substances

Antigens, Viral
RNA, Viral