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, 11 (6), 962-5

Community-associated Methicillin-Resistant Staphylococcus Aureus, Switzerland


Community-associated Methicillin-Resistant Staphylococcus Aureus, Switzerland

Stephan Harbarth et al. Emerg Infect Dis.


Two case-control studies evaluated the prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) carriage at hospital admission and characteristics of patients with CA-MRSA. Among 14,253 patients, CA-MRSA prevalence was 0.9/1,000 admissions. Although 5 CA-MRSA isolates contained Panton-Valentine leukocidin, only 1 patient had a previous skin infection. No easily modifiable risk factor for CA-MRSA was identified.


Analysis of genotyping patterns, multilocus sequence typing (ST) results, presence of Panton-Valentine leukocidin (PVL), staphylococcal cassette chromosome mec (SCCmec) type, and country of patient origin of 13 community-associated, methicillin-resistant Staphylococcus aureus isolates (CA-MRSA). The dendrogram illustrates the genetic relatedness of the 13 CA-MRSA in comparison to 1) 2 nosocomial MRSA isolates representing the prevailing endemic strain in the Geneva healthcare setting (strains B5-63, B5-64) and to 2) profiles obtained for strains MW2 and HT20030642 from the United States, 2 closely related CA-MRSA isolates used as controls.

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