Acute tumor lysis syndrome triggered by zoledronic Acid in a patient with metastatic lung adenocarcinoma

Med Oncol. 2005;22(2):203-6. doi: 10.1385/MO:22:2:203.

Abstract

We report the case of a 52-yr-old man with metastatic lung adenocarcinoma who developed tumor lysis syndrome after administration of zoledronic acid. Tumor lysis syndrome in solid tumors and the antitumor effect of the zolendronic acid are discussed in light of the pertinent literature.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / secondary*
  • Diphosphonates / adverse effects*
  • Humans
  • Imidazoles / adverse effects*
  • Lung Neoplasms / pathology*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Tumor Lysis Syndrome / blood
  • Tumor Lysis Syndrome / diagnosis
  • Tumor Lysis Syndrome / etiology*
  • Zoledronic Acid

Substances

  • Diphosphonates
  • Imidazoles
  • Zoledronic Acid