B-RAF and melanocytic neoplasia

J Am Acad Dermatol. 2005 Jul;53(1):108-14. doi: 10.1016/j.jaad.2005.04.013.


High frequency of B-RAF gene mutations has recently been identified in benign melanocytic nevi and melanoma. This review focuses on clinical studies that evaluate the role of B-RAF in melanocytic neoplasia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Humans
  • Melanoma / classification
  • Melanoma / genetics*
  • Mutation
  • Nevus, Pigmented / genetics
  • Proto-Oncogene Proteins B-raf / genetics*
  • Skin Neoplasms / classification
  • Skin Neoplasms / genetics*


  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf