Factors and interventions influencing health-related quality of life in patients with heart failure: a review of the literature

Eur J Cardiovasc Nurs. 2006 Mar;5(1):5-15. doi: 10.1016/j.ejcnurse.2005.04.011. Epub 2005 Jun 20.


Introduction: Because of the lack of a cure for patients with chronic heart failure (HF), there has been a progressive interest in the use of health-related quality of life (Hr-QoL) as complementary end-point to mortality and morbidity.

Aim: The aim of this review was from a nursing perspective to describe Hr-QoL and the influencing factors of Hr-QoL, as well as to identify interventions aimed at influencing Hr-QoL in HF patients.

Method: Medline, Cinahl and PsycInfo databases were searched from 1995 to 2004. A total of 58 papers were included.

Results: HF symptoms and activity status influence Hr-QoL negatively. However, several individual characteristics such as personality, gender and age must also be taken into consideration because different values might exist regarding what constitutes a good Hr-QoL. Nurse led interventions based on education, support and exercise can influence Hr-QoL positively. There is also a need of more studies about the effects of depression, sleep disturbances, support as well as education on Hr-QoL. There is also a need of exercise studies with larger sample sizes and older patients in higher NYHA classes.

Conclusion: Several individual factors impact Hr-QoL, therefore, must nursing interventions are individually adapted to the patient's resources.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Activities of Daily Living
  • Adaptation, Psychological
  • Age Factors
  • Attitude to Health*
  • Cost of Illness
  • Depression / etiology
  • Dyspnea / etiology
  • Exercise
  • Fatigue / etiology
  • Health Services Needs and Demand
  • Health Status*
  • Heart Failure / complications
  • Heart Failure / nursing
  • Heart Failure / psychology*
  • Humans
  • Nursing Assessment
  • Nursing Methodology Research
  • Patient Education as Topic
  • Quality of Life / psychology*
  • Risk Factors
  • Severity of Illness Index
  • Sex Factors
  • Sickness Impact Profile
  • Sleep Wake Disorders / etiology
  • Social Support