How close are we to understanding v1?

Neural Comput. 2005 Aug;17(8):1665-99. doi: 10.1162/0899766054026639.


A wide variety of papers have reviewed what is known about the function of primary visual cortex. In this review, rather than stating what is known, we attempt to estimate how much is still unknown about V1 function. In particular, we identify five problems with the current view of V1 that stem largely from experimental and theoretical biases, in addition to the contributions of nonlinearities in the cortex that are not well understood. Our purpose is to open the door to new theories, a number of which we describe, along with some proposals for testing them.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bias
  • Humans
  • Models, Neurological*
  • Neurons / classification
  • Neurons / physiology*
  • Nonlinear Dynamics
  • Visual Cortex / cytology*
  • Visual Cortex / physiology*
  • Visual Pathways / physiology*