Vitamin C for preventing and treating the common cold

PLoS Med. 2005 Jun;2(6):e168; quiz e217. doi: 10.1371/journal.pmed.0020168. Epub 2005 Jun 28.


Whether vitamin C has an effect on the common cold has been a subject of controversy for at least 60 years. What does the evidence show?

Publication types

  • Meta-Analysis

MeSH terms

  • Ascorbic Acid / therapeutic use*
  • Common Cold / drug therapy
  • Common Cold / prevention & control*
  • Humans
  • Randomized Controlled Trials as Topic


  • Ascorbic Acid