The lessons of Vioxx--drug safety and sales

N Engl J Med. 2005 Jun 23;352(25):2576-8. doi: 10.1056/NEJMp058136.
No abstract available

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Arthritis / drug therapy
  • Cyclooxygenase Inhibitors / adverse effects*
  • Cyclooxygenase Inhibitors / therapeutic use
  • Drug Evaluation / legislation & jurisprudence
  • Drug Evaluation / standards
  • Drug Industry*
  • Gastrointestinal Diseases / chemically induced
  • Humans
  • Lactones / adverse effects*
  • Lactones / therapeutic use
  • Marketing* / economics
  • Myocardial Infarction / chemically induced*
  • Naproxen / therapeutic use
  • Scientific Misconduct*
  • Sulfones / adverse effects*
  • Sulfones / therapeutic use
  • United States

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors
  • Lactones
  • Sulfones
  • rofecoxib
  • Naproxen