Colonic stricture secondary to hemolytic uremic syndrome caused by Escherichia coli O-157

Pediatr Nephrol. 2005 Oct;20(10):1496-9. doi: 10.1007/s00467-005-1996-4. Epub 2005 Jun 23.


Shiga toxin-producing Escherichia coli (E. coli) is known to be one of the main causes of hemolytic uremic syndrome (HUS). Of the secondary complications of HUS, colonic stricture is relatively rare. We herein report on a Japanese girl that demonstrated sigmoid colon stricture secondary to HUS caused by an infection of E. coli O-157. Severe HUS occurred after the E. coli O-157 infection, so hemodialysis was performed due to renal failure. However, 1 month after recovery from HUS, abdominal symptoms occurred. A contrast study in the colon revealed a sigmoid colon stricture. The stricture was operatively resected. Thereafter, her postoperative course was uneventful. We also review the occurrence of this complication secondary to HUS in the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Colonic Diseases / diagnostic imaging
  • Colonic Diseases / etiology*
  • Colonic Diseases / pathology
  • Escherichia coli Infections / complications*
  • Escherichia coli O157*
  • Female
  • Hemolytic-Uremic Syndrome / complications*
  • Hemolytic-Uremic Syndrome / microbiology*
  • Humans
  • Intestinal Obstruction / diagnostic imaging
  • Intestinal Obstruction / etiology*
  • Intestinal Obstruction / pathology
  • Radiography