Differential drug binding by the highly conserved Plasmodium falciparum thymidylate synthase

Mol Biochem Parasitol. 2005 Sep;143(1):121-4. doi: 10.1016/j.molbiopara.2005.02.016.
No abstract available

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antimalarials / pharmacokinetics*
  • Binding Sites
  • Conserved Sequence
  • Humans
  • Kinetics
  • Plasmodium falciparum / enzymology*
  • Protozoan Proteins / chemistry
  • Protozoan Proteins / metabolism
  • Thymidylate Synthase / chemistry*
  • Thymidylate Synthase / metabolism*

Substances

  • Antimalarials
  • Protozoan Proteins
  • Thymidylate Synthase